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ABOUT US > People > Team > Rabih Talhouk

 

 

 
Dr Rabih Talhouk's laboratory work focuses on two main lines of research. The first has to do with deciphering the mechanisms, at the molecular level, that regulate the interaction of the cell with its microenvironment. For that, different mammary cell culture models are used. The role of the gap junctions, connexins, and their associated proteins, in regulating mammary growth, development and mammary epithelial cell differentiation is investigated. The second line of research, investigates the claimed anti-inflammatory bioactivities in Lebanese indigenous plants commonly used in folk medicine. An endotoxin treated mammary cell culture model that mimics inflammation and in vivo animal models are used for that purpose.
Research Activities
“ The work in my laboratory focuses on two main lines of research. The first line of research, investigates the claimed anti-inflammatory bioactivities in Lebanese indigenous plants commonly used in folk medicine. An endotoxin treated mammary epithelial cell culture model that mimics inflammation and in vivo animal models are used for that purpose. The cell culture model is one that can differentiate in culture and when treated with endotoxin it loses its differentiated phenotype. Both, the cell culture model and the in vivo model are used in concert to determine cellular targets and mechanisms of action of potential anti-inflammatory plant derived bioactivities. The second line of research in my laboratory has to do with deciphering the mechanisms, at the molecular level, that regulate the interaction of the cell with its microenvironment. ”
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Contact: rtalhouk@aub.edu.lb
 

 

 

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